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Before we explain the prognosis and possible outcomes of the chronic lymphocytic leukemia it is important to understand what leukemia is at all when you’re diagnosed with some serious conditions such as leukemia it is really important to understand what that is and what to expect and that is often not the case because doctors simply don’t have enough of time to talk to their patients and explain everything in details this here is a bone supposedly I know it’s not a great representation of a bone not a perfect illustration but let’s assume it is a bone well this over here inside of that bone is the bone marrow and that spongy tissue is the place where blood cells are created and that is exactly where this cancer is located at leukemia is a cancer that involves bone marrow and problems and consequences of this cancer can be seen in the peripheral blood as we said that is the place where blood is created obviously if there is a cancer here in the creation of the blood cells well we should be able to tell that something is wrong by just analyzing blood the peripheral blood in their lab results this over here is a monoclonal B cell lymphocyte and that what we can see here on the surface of this cell are the membrane proteins these membrane proteins help us diagnose this condition these proteins are marked by numbers such as cd20 or cd20 19 plus or c23 plus as well as cd5 Plus and while simply analyzing the lab results can help us see that there’s something wrong these proteins can actually help us pinpoint the condition that is causing the issues and the symptoms these proteins on the surface of the cell membranes can be identified using a method called flow cytometry and that way we can really not only see how many lymphocytes they are but also what kind of lymphocytes are present this is an incredible source of information that help us diagnose chronic lymphocytic leukemia but early treatment does not really help one live longer in fact in this condition it is slightly different first and foremost we should cause no harm to the patient and I’m going to repeat that no harm to the patient and excessive therapy without true need for it can indeed cause more damage than help normally we should also care about the quality of life of the patient and it is important how the patient is feeling and his well-being therefore applying a therapy in this case should be considered if certain criteria is fulfilled because if we know that the therapy will cause more damage than help we should not apply it of course one such criteria is the decree a decrease of hemoglobin below 10 grams per deciliter and a decrease of thrombocytes count below 100 000 units per microliter this is a clear indication that the therapy should start there are other indications when these therapies should start even when we decide to start a therapy we have to understand the patient and the patient’s condition a sick patient can survive a much more aggressive therapy than a patient who’s old and fragile and already has other diseases so we can learn today that starting a therapy and also what kind of therapy are decisions that can be made first and foremost with good Diagnostics and very professional interpretation of these Diagnostics an answer about what kind of therapy and when the therapy should start almost always requires a second opinion so that we make sure we do not actually damage and harm the patient that is already suffering that can really and unfortunately happen and it does happen if you have more questions about chronic lymphocytic leukemia then go to symptomsky.com/help/CLL but if you’re a doctor and you want to make videos like these then go to anatomsky.com and both of you can actually subscribe to this Channel and help us reach more people who suffer or assume they suffer from chronic lymphocytic leukemia

Lower vitamin D is also associated with lower immune readiness of the body and therefore patients are more easily infected and they can more easily end up having lethal conditions such as sepsis.

But besides these consequences of vitamin D deficiency, the causes of it, the underlying causes for vitamin D deficiency can be very dangerous and lethal as well.

Vitamin D production depends on multiple organs and that includes skin that gets some light exposure, but it also includes gastrointestinal tract and besides that also liver and kidneys.

So, depression itself has to be investigated as well.

Not every depression is simply psychogenic.

These dangerous and organic causes for depression or vitamin D deficiency have to be ruled out.

But because of all of these issues I’ve mentioned and illustrated, it is not smart to simply assume that only sunlight exposure or a pill can fix it. A skilled doctor should be able to recognize signs and symptoms that indicated something might be wrong. And this might not only increase the patient’s life quality if these causes are treated, but it can also save the patient’s life.

Vitamin D production depends on multiple organs and that includes skin that gets sunlight exposure,

but it also includes gastrointestinal tract and besides that also liver and kidneys.

So, the most common cause we think about when it comes to vitamin D deficiency is this lack of sunlight exposure.

But chronic inflammatory bowel diseases can cause vitamin D deficiency as well and so can chronic kidney disease.

Vitamin D deficiency is extremely common in liver failure patients.